Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to myofibroblasts that produce high levels of collagen, leading to concomitantly loss of lung elasticity and function. Recent...

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Publicat a:Cell Death Dis
Autors principals: Wei, Peng, Xie, Yan, Abel, Peter W., Huang, Yapei, Ma, Qin, Li, Linghai, Hao, Junfeng, Wolff, Dennis W., Wei, Taotao, Tu, Yaping
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739313/
https://ncbi.nlm.nih.gov/pubmed/31511493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1873-x
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