Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to myofibroblasts that produce high levels of collagen, leading to concomitantly loss of lung elasticity and function. Recent...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wei, Peng, Xie, Yan, Abel, Peter W., Huang, Yapei, Ma, Qin, Li, Linghai, Hao, Junfeng, Wolff, Dennis W., Wei, Taotao, Tu, Yaping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739313/
https://ncbi.nlm.nih.gov/pubmed/31511493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1873-x
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