Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis

Transforming growth factor (TGF)-β1, a main profibrogenic cytokine in the progression of idiopathic pulmonary fibrosis (IPF), induces differentiation of pulmonary fibroblasts to myofibroblasts that produce high levels of collagen, leading to concomitantly loss of lung elasticity and function. Recent...

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Foilsithe in:Cell Death Dis
Main Authors: Wei, Peng, Xie, Yan, Abel, Peter W., Huang, Yapei, Ma, Qin, Li, Linghai, Hao, Junfeng, Wolff, Dennis W., Wei, Taotao, Tu, Yaping
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739313/
https://ncbi.nlm.nih.gov/pubmed/31511493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1873-x
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