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The Tyrosine Kinase Pyk2 Contributes to Complement-Mediated Phagocytosis in Murine Macrophages

Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase (FAK) family and is mainly expressed in neuronal and hematopoietic cells. As FAK family members are involved in signaling connections downstream of integrins, we studied the role of Pyk2 in complement-receptor 3 (CR3, als...

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Bibliographische Detailangaben
Veröffentlicht in:J Innate Immun
Hauptverfasser: Paone, Christoph, Rodrigues, Natalie, Ittner, Ella, Santos, Carina, Buntru, Alexander, Hauck, Christof R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738876/
https://ncbi.nlm.nih.gov/pubmed/26848986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000442944
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