The Tyrosine Kinase Pyk2 Contributes to Complement-Mediated Phagocytosis in Murine Macrophages

Proline-rich tyrosine kinase 2 (Pyk2) is a member of the focal adhesion kinase (FAK) family and is mainly expressed in neuronal and hematopoietic cells. As FAK family members are involved in signaling connections downstream of integrins, we studied the role of Pyk2 in complement-receptor 3 (CR3, als...

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Udgivet i:J Innate Immun
Main Authors: Paone, Christoph, Rodrigues, Natalie, Ittner, Ella, Santos, Carina, Buntru, Alexander, Hauck, Christof R.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738876/
https://ncbi.nlm.nih.gov/pubmed/26848986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000442944
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