Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages

Phagocytosis of the opportunistic fungal pathogen Candida albicans by cells of the innate immune system is vital to prevent infection. Dectin-1 is the major phagocytic receptor involved in anti-fungal immunity. We identify two new interacting proteins of Dectin-1 in macrophages, Bruton's Tyrosi...

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Detalhes bibliográficos
Main Authors: Strijbis, Karin, Tafesse, Fikadu G., Fairn, Gregory D., Witte, Martin D., Dougan, Stephanie K., Watson, Nicki, Spooner, Eric, Esteban, Alexandre, Vyas, Valmik K., Fink, Gerald R., Grinstein, Sergio, Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694848/
https://ncbi.nlm.nih.gov/pubmed/23825946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003446
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