Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

The ability of phagocytes to clear pathogens is an essential attribute of the innate immune response. The role of signaling lipid molecules such as phosphoinositides is well established, but the role of membrane sphingolipids in phagocytosis is largely unknown. Using a genetic approach and small mol...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Autores principales: Tafesse, Fikadu G., Rashidfarrokhi, Ali, Schmidt, Florian I., Freinkman, Elizaveta, Dougan, Stephanie, Dougan, Michael, Esteban, Alexandre, Maruyama, Takeshi, Strijbis, Karin, Ploegh, Hidde L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592247/
https://ncbi.nlm.nih.gov/pubmed/26431038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005188
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