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2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells

Microbial RNA is an important stimulator of innate immune responses. Differences in posttranscriptional RNA modification profiles enable the immune system to discriminate between self and non-self nucleic acids. This principle may be exploited by certain bacteria to circumvent immune cell activation...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Rimbach, Katharina, Kaiser, Steffen, Helm, Mark, Dalpke, Alexander H., Eigenbrod, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738864/
https://ncbi.nlm.nih.gov/pubmed/25823462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000375460
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