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VPS13D Gene Variant Is Associated with Altered IL-6 Production and Mortality in Septic Shock
BACKGROUND: Genetic variations contribute to septic shock mortality. To discover a novel locus, we performed in vitro genome-wide association studies (GWAS) and further tested the result in a cohort of septic shock patients. METHODS: Two in vitro GWAS using a quantitative trait locus analysis of sti...
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| Veröffentlicht in: | J Innate Immun |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
S. Karger AG
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738836/ https://ncbi.nlm.nih.gov/pubmed/25896417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381265 |
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