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Non-receptor tyrosine kinase signaling in autoimmunity and therapeutic implications

Autoimmune diseases are characterized by impaired immune tolerance towards self-antigens, leading to enhanced immunity to self by dysfunctional B cells and/or T cells. The activation of these cells is controlled by non-receptor tyrosine kinases (NRTKs), which are critical mediators of antigen recept...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Ther
Hauptverfasser: Solouki, Sabrina, August, Avery, Huang, Weishan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738557/
https://ncbi.nlm.nih.gov/pubmed/31082431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.05.008
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