Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Breast cancer is a multifactorial disease and driven by aberrant regulation of cell signaling pathways due to the acquisition of genetic and epigenetic changes. An array of growth factors and their receptors is involved in cancer development and metastasis. Receptor Tyrosine Kinases (RTKs) constitut...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Principais autores: Butti, Ramesh, Das, Sumit, Gunasekaran, Vinoth Prasanna, Yadav, Amit Singh, Kumar, Dhiraj, Kundu, Gopal C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817867/
https://ncbi.nlm.nih.gov/pubmed/29455658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0797-x
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