Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Breast cancer is a multifactorial disease and driven by aberrant regulation of cell signaling pathways due to the acquisition of genetic and epigenetic changes. An array of growth factors and their receptors is involved in cancer development and metastasis. Receptor Tyrosine Kinases (RTKs) constitut...

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Foilsithe in:Mol Cancer
Main Authors: Butti, Ramesh, Das, Sumit, Gunasekaran, Vinoth Prasanna, Yadav, Amit Singh, Kumar, Dhiraj, Kundu, Gopal C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Review
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817867/
https://ncbi.nlm.nih.gov/pubmed/29455658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0797-x
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