Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Breast cancer is a multifactorial disease and driven by aberrant regulation of cell signaling pathways due to the acquisition of genetic and epigenetic changes. An array of growth factors and their receptors is involved in cancer development and metastasis. Receptor Tyrosine Kinases (RTKs) constitut...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer
Hoofdauteurs: Butti, Ramesh, Das, Sumit, Gunasekaran, Vinoth Prasanna, Yadav, Amit Singh, Kumar, Dhiraj, Kundu, Gopal C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817867/
https://ncbi.nlm.nih.gov/pubmed/29455658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0797-x
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