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Attenuated BK channel function promotes overactive bladder in a rat model of obesity

Overactive bladder (OAB) is mostly observed in obese individuals, and is associated with enhanced excitability and contractility of the detrusor smooth muscle (DSM). Large-conductance voltage- and Ca(2+)-activated K(+) (BK) channels reduce the excitability and contractility of the DSM. We tested whe...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Li, Ning, Ding, Honglin, Zhang, Peng, Li, Zizheng, Liu, Yili, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738405/
https://ncbi.nlm.nih.gov/pubmed/31480021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102182
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