Augmented bladder urothelial polyamine signaling and block of BK channel in the pathophysiology of overactive bladder syndrome

Overactive bladder syndrome (OAB) is an idiopathic condition characterized by urinary urgency and urge incontinence. Detrusor overactivity has been traditionally described as the physiologic mechanism for OAB. However, the bladder urothelium (BU) may also be involved in the pathophysiology. This stu...

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Detalhes bibliográficos
Main Authors: Li, Mingkai, Sun, Yan, Simard, J. Marc, Wang, Jian-Ying, Chai, Toby C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793056/
https://ncbi.nlm.nih.gov/pubmed/19812367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00259.2009
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