Augmented bladder urothelial polyamine signaling and block of BK channel in the pathophysiology of overactive bladder syndrome

Overactive bladder syndrome (OAB) is an idiopathic condition characterized by urinary urgency and urge incontinence. Detrusor overactivity has been traditionally described as the physiologic mechanism for OAB. However, the bladder urothelium (BU) may also be involved in the pathophysiology. This stu...

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Autors principals: Li, Mingkai, Sun, Yan, Simard, J. Marc, Wang, Jian-Ying, Chai, Toby C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2009
Matèries:
Receptors and Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793056/
https://ncbi.nlm.nih.gov/pubmed/19812367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00259.2009
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