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Erosion of telomeric single-stranded overhang in patients with aplastic anaemia carrying telomerase complex mutations
BACKGROUND: Loss-of-function mutations in telomerase complex genes reduce telomerase activity and shorten overall telomere length in leucocytes, and they can clinically manifest as bone marrow failure (aplastic anaemia and dyskeratosis congenita) and familial pulmonary fibrosis. Telomeres are consti...
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| Publicado no: | Eur J Clin Invest |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738339/ https://ncbi.nlm.nih.gov/pubmed/19674077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2362.2009.02209.x |
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