Platelet-Dense Granules Worsen Pre-Infection Thrombocytopenia during Gram-Negative Pneumonia-Derived Sepsis

Platelet-dense (δ) granules are important for platelet function. Platelets contribute to host defense and vascular integrity during pneumonia and sepsis, and δ granule products, including adenosine diphosphate (ADP), can influence inflammatory responses. We therefore aimed to study the role of plate...

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Vydáno v:J Innate Immun
Hlavní autoři: Claushuis, Theodora A.M., de Vos, Alex F., Roelofs, Joris J.T.H., de Boer, Onno J., van 't Veer, Cornelis, van der Poll, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738263/
https://ncbi.nlm.nih.gov/pubmed/30557883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000494147
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