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A novel vaccine strategy to overcome poor immunogenicity of avian influenza vaccines through mobilization of memory CD4 T cells established by seasonal influenza
Avian influenza vaccines exhibit poor immunogenicity in humans. We hypothesized that one factor underlying weak B cell responses was sequence divergence between avian and seasonal influenza hemagglutinin proteins limiting availability of adequate CD4 T cell help. To test this, a novel chimeric hemag...
Shranjeno v:
| izdano v: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737897/ https://ncbi.nlm.nih.gov/pubmed/31399519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900819 |
| Oznake: |
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