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A novel vaccine strategy to overcome poor immunogenicity of avian influenza vaccines through mobilization of memory CD4 T cells established by seasonal influenza
Avian influenza vaccines exhibit poor immunogenicity in humans. We hypothesized that one factor underlying weak B cell responses was sequence divergence between avian and seasonal influenza hemagglutinin proteins limiting availability of adequate CD4 T cell help. To test this, a novel chimeric hemag...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6737897/ https://ncbi.nlm.nih.gov/pubmed/31399519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900819 |
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