Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source

BACKGROUND: The trans-fat containing AMLN (amylin liver non-alcoholic steatohepatitis, NASH) diet has been extensively validated in C57BL/6J mice with or without the Lep(ob)/Lep(ob) (ob/ob) mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2019
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737317/
https://ncbi.nlm.nih.gov/pubmed/31543682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i33.4904
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