Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound‐associated extracellular matrix: implications for cancer therapy

Antzeko izenburuak

• Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin
  nork: McNitt, Dudley H., et al.
  Argitaratua: (2018)
• Expression and Purification of Collagen-Like Proteins of Group A Streptococcus
  nork: Lukomski, Slawomir, et al.
  Argitaratua: (2020)
• Scl1, the multifunctional adhesin of group A Streptococcus selectively binds cellular fibronectin and laminin, and mediates pathogen internalization by human cells
  nork: Caswell, Clayton C., et al.
  Argitaratua: (2009)
• The group A streptococcal collagen-like protein 1, Scl1, mediates biofilm formation by targeting the EDA-containing variant of cellular fibronectin expressed in wounded tissue
  nork: Oliver-Kozup, Heaven, et al.
  Argitaratua: (2012)
• Unique Footprint in the scl1.3 Locus Affects Adhesion and Biofilm Formation of the Invasive M3-Type Group A Streptococcus
  nork: Bachert, Beth A., et al.
  Argitaratua: (2016)