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Surface-exposed loops and an acidic patch in the Scl1 protein of group A Streptococcus enable Scl1 binding to wound-associated fibronectin

Keratinized epidermis constitutes a powerful barrier of the mucosa and skin, effectively preventing bacterial invasion, unless it is wounded and no longer protective. Wound healing involves deposition of distinct extracellular matrix (ECM) proteins enriched in cellular fibronectin (cFn) isoforms con...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: McNitt, Dudley H., Choi, Soo Jeon, Keene, Douglas R., Van De Water, Livingston, Squeglia, Flavia, Berisio, Rita, Lukomski, Slawomir
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961034/
https://ncbi.nlm.nih.gov/pubmed/29615492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002250
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