Adaptation of the group A Streptococcus adhesin Scl1 to bind fibronectin type III repeats within wound‐associated extracellular matrix: implications for cancer therapy

The human‐adapted pathogen group A Streptococcus (GAS) utilizes wounds as portals of entry into host tissue, wherein surface adhesins interact with the extracellular matrix, enabling bacterial colonization. The streptococcal collagen‐like protein 1 (Scl1) is a major adhesin of GAS that selectively b...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: McNitt, Dudley H., Choi, Soo Jeon, Allen, Jessica L., Hames, River A., Weed, Scott A., Van De Water, Livingston, Berisio, Rita, Lukomski, Slawomir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736723/
https://ncbi.nlm.nih.gov/pubmed/31145503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14317
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