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Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules
The fibrillary aggregation of the protein alpha synuclein (Asyn) is a hallmark of Parkinson’s disease, and the identification of small molecule binding sites on fibrils is essential to the development of diagnostic imaging probes. A series of molecular modelling, photoaffinity labeling, mass spectro...
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| Udgivet i: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736640/ https://ncbi.nlm.nih.gov/pubmed/29750499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00177 |
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