Llwytho...

Integrin α4β1 and TLR4 Cooperate to Induce Fibrotic Gene Expression in Response to Fibronectin’s EDA Domain

Alternative splicing of fibronectin increases expression of the EDA(+) isoform of fibronectin (EDA(+)Fn), a damage-associated molecular pattern (DAMP) molecule, which promotes fibro-inflammatory disease through the activation of toll-like receptors (TLR). Our studies indicate that the fibronectin ED...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Invest Dermatol
Prif Awduron: Kelsh-Lasher, Rhiannon M., Ambesi, Anthony, Bertram, Cedya, McKeown-Longo, Paula J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736604/
https://ncbi.nlm.nih.gov/pubmed/28842322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.08.005
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