Φορτώνει......
Population pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing
OBJECTIVES: The current WHO weight-based dosing recommendations for efavirenz result in a wide variability of drug exposure in children. Our objectives are to characterize the effects of rifampicin- and isoniazid-containing anti-TB therapy and CYP2B6 activity on efavirenz concentrations in children,...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Antimicrob Chemother |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736323/ https://ncbi.nlm.nih.gov/pubmed/31243456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz238 |
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