Sex differences in the genetic predictors of Alzheimer’s pathology

Autopsy measures of Alzheimer’s disease neuropathology have been leveraged as endophenotypes in previous genome-wide association studies (GWAS). However, despite evidence of sex differences in Alzheimer’s disease risk, sex-stratified models have not been incorporated into previous GWAS analyses. We...

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Udgivet i:Brain
Main Authors: Dumitrescu, Logan, Barnes, Lisa L, Thambisetty, Madhav, Beecham, Gary, Kunkle, Brian, Bush, William S, Gifford, Katherine A, Chibnik, Lori B, Mukherjee, Shubhabrata, De Jager, Philip L, Kukull, Walter, Crane, Paul K, Resnick, Susan M, Keene, C Dirk, Montine, Thomas J, Schellenberg, Gerard D, Deming, Yuetiva, Chao, Michael J, Huentelman, Matt, Martin, Eden R, Hamilton-Nelson, Kara, Shaw, Leslie M, Trojanowski, John Q, Peskind, Elaine R, Cruchaga, Carlos, Pericak-Vance, Margaret A, Goate, Alison M, Cox, Nancy J, Haines, Jonathan L, Zetterberg, Henrik, Blennow, Kaj, Larson, Eric B, Johnson, Sterling C, Albert, Marilyn, Bennett, David A, Schneider, Julie A, Jefferson, Angela L, Hohman, Timothy J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736148/
https://ncbi.nlm.nih.gov/pubmed/31497858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz206
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