Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

IMPORTANCE: The strongest genetic risk factor for Alzheimer disease (AD), the apolipoprotein E (APOE) gene, has a stronger association among women compared with men. Yet limited work has evaluated the association between APOE alleles and markers of AD neuropathology in a sex-specific manner. OBJECTI...

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Vydáno v:JAMA Neurol
Hlavní autoři: Hohman, Timothy J., Dumitrescu, Logan, Barnes, Lisa L., Thambisetty, Madhav, Beecham, Gary, Kunkle, Brian, Gifford, Katherine A., Bush, William S., Chibnik, Lori B., Mukherjee, Shubhabrata, De Jager, Philip L., Kukull, Walter, Crane, Paul K., Resnick, Susan M., Keene, C. Dirk, Montine, Thomas J., Schellenberg, Gerard D., Haines, Jonathan L., Zetterberg, Henrik, Blennow, Kaj, Larson, Eric B., Johnson, Sterling C., Albert, Marilyn, Bennett, David A., Schneider, Julie A., Jefferson, Angela L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2018
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142927/
https://ncbi.nlm.nih.gov/pubmed/29801024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.0821
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