Sex differences in the genetic predictors of Alzheimer’s pathology

Autopsy measures of Alzheimer’s disease neuropathology have been leveraged as endophenotypes in previous genome-wide association studies (GWAS). However, despite evidence of sex differences in Alzheimer’s disease risk, sex-stratified models have not been incorporated into previous GWAS analyses. We...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Dumitrescu, Logan, Barnes, Lisa L, Thambisetty, Madhav, Beecham, Gary, Kunkle, Brian, Bush, William S, Gifford, Katherine A, Chibnik, Lori B, Mukherjee, Shubhabrata, De Jager, Philip L, Kukull, Walter, Crane, Paul K, Resnick, Susan M, Keene, C Dirk, Montine, Thomas J, Schellenberg, Gerard D, Deming, Yuetiva, Chao, Michael J, Huentelman, Matt, Martin, Eden R, Hamilton-Nelson, Kara, Shaw, Leslie M, Trojanowski, John Q, Peskind, Elaine R, Cruchaga, Carlos, Pericak-Vance, Margaret A, Goate, Alison M, Cox, Nancy J, Haines, Jonathan L, Zetterberg, Henrik, Blennow, Kaj, Larson, Eric B, Johnson, Sterling C, Albert, Marilyn, Bennett, David A, Schneider, Julie A, Jefferson, Angela L, Hohman, Timothy J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736148/
https://ncbi.nlm.nih.gov/pubmed/31497858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz206
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