Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

IMPORTANCE: The strongest genetic risk factor for Alzheimer disease (AD), the apolipoprotein E (APOE) gene, has a stronger association among women compared with men. Yet limited work has evaluated the association between APOE alleles and markers of AD neuropathology in a sex-specific manner. OBJECTI...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Hohman, Timothy J., Dumitrescu, Logan, Barnes, Lisa L., Thambisetty, Madhav, Beecham, Gary, Kunkle, Brian, Gifford, Katherine A., Bush, William S., Chibnik, Lori B., Mukherjee, Shubhabrata, De Jager, Philip L., Kukull, Walter, Crane, Paul K., Resnick, Susan M., Keene, C. Dirk, Montine, Thomas J., Schellenberg, Gerard D., Haines, Jonathan L., Zetterberg, Henrik, Blennow, Kaj, Larson, Eric B., Johnson, Sterling C., Albert, Marilyn, Bennett, David A., Schneider, Julie A., Jefferson, Angela L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142927/
https://ncbi.nlm.nih.gov/pubmed/29801024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2018.0821
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