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SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170
SIRT6 is critical for activating transcription of Nuclear factor (erythroid-derived 2)-like 2 (NRF2) responsive genes during oxidative stress. However, while the mechanism of SIRT6-mediated silencing is well understood, the mechanism of SIRT6-mediated transcriptional activation is unknown. Here, we...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6736037/ https://ncbi.nlm.nih.gov/pubmed/31216030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz528 |
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