CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice

More than 1000 genes are predicted to be predominantly expressed in mouse testis, yet many of them remain unstudied in terms of their roles in spermatogenesis and sperm function and their essentiality in male reproduction. Since individually indispensable factors can provide important implications f...

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Veröffentlicht in:Biol Reprod
Hauptverfasser: Lu, Yonggang, Oura, Seiya, Matsumura, Takafumi, Oji, Asami, Sakurai, Nobuyuki, Fujihara, Yoshitaka, Shimada, Keisuke, Miyata, Haruhiko, Tobita, Tomohiro, Noda, Taichi, Castaneda, Julio M, Kiyozumi, Daiji, Zhang, Qian, Larasati, Tamara, Young, Samantha A M, Kodani, Mayo, Huddleston, Caitlin A, Robertson, Matthew J, Coarfa, Cristian, Isotani, Ayako, Aitken, R John, Okabe, Masaru, Matzuk, Martin M, Garcia, Thomas X, Ikawa, Masahito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735960/
https://ncbi.nlm.nih.gov/pubmed/31201419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz103
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