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Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis
Mutations causing amyotrophic lateral sclerosis (ALS) clearly implicate ubiquitously expressed and predominantly nuclear RNA binding proteins, which form pathological cytoplasmic inclusions in this context. However, the possibility that wild-type RNA binding proteins mislocalize without necessarily...
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| Publicado no: | Brain |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735815/ https://ncbi.nlm.nih.gov/pubmed/31368485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz217 |
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