Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

Fused in sarcoma (FUS) and TAR DNA-binding protein 43 (TDP-43) are RNA-binding proteins pathogenetically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), but it is not known if they regulate the same transcripts. We addressed this question using crosslinkin...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rogelj, Boris, Easton, Laura E., Bogu, Gireesh K., Stanton, Lawrence W., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Sugimoto, Yoichiro, Modic, Miha, Haberman, Nejc, Tollervey, James, Fujii, Ritsuko, Takumi, Toru, Shaw, Christopher E., Ule, Jernej
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2012
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429604/
https://ncbi.nlm.nih.gov/pubmed/22934129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00603
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