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Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
Fused in sarcoma (FUS) and TAR DNA-binding protein 43 (TDP-43) are RNA-binding proteins pathogenetically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), but it is not known if they regulate the same transcripts. We addressed this question using crosslinkin...
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| Main Authors: | , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429604/ https://ncbi.nlm.nih.gov/pubmed/22934129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00603 |
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