Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice

The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock that is synchronized by the SCN. To determine whether the adrenal clock modulates GC responses to stress, experiments used female and male Cyp11A1(Cre/+)::Bmal1(Fl/Fl)...

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Publicat a:Endocrinology
Autors principals: Engeland, William C, Massman, Logan, Miller, Lauren, Leng, Sining, Pignatti, Emanuele, Pantano, Lorena, Carlone, Diana L, Kofuji, Paulo, Breault, David T
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735739/
https://ncbi.nlm.nih.gov/pubmed/31398249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00357
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