Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice

The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock that is synchronized by the SCN. To determine whether the adrenal clock modulates GC responses to stress, experiments used female and male Cyp11A1(Cre/+)::Bmal1(Fl/Fl)...

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Publicado en:Endocrinology
Main Authors: Engeland, William C, Massman, Logan, Miller, Lauren, Leng, Sining, Pignatti, Emanuele, Pantano, Lorena, Carlone, Diana L, Kofuji, Paulo, Breault, David T
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2019
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735739/
https://ncbi.nlm.nih.gov/pubmed/31398249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00357
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