Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency

Several lines of evidence support the occurrence of cross-regulation between the endocytic pathway and autophagy, but the molecular mechanisms regulating this process are not well-understood. Here, we show that the calcium sensor UNC13D regulates the molecular mechanism of late endosomal trafficking...

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Опубликовано в: :Autophagy
Главные авторы: Zhang, Jinzhong, He, Jing, Johnson, Jennifer L., Napolitano, Gennaro, Ramadass, Mahalakshmi, Rahman, Farhana, Catz, Sergio D.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2019
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735675/
https://ncbi.nlm.nih.gov/pubmed/30892133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1596475
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