Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses

The molecular mechanisms that regulate late endosomal maturation and function are not completely elucidated, and direct evidence of a calcium sensor is lacking. Here we identify a novel mechanism of late endosomal maturation that involves a new molecular interaction between the tethering factor Munc...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: He, Jing, Johnson, Jennifer L., Monfregola, Jlenia, Ramadass, Mahalakshmi, Pestonjamasp, Kersi, Napolitano, Gennaro, Zhang, Jinzhong, Catz, Sergio D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751605/
https://ncbi.nlm.nih.gov/pubmed/26680738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0283
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