CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD(+)/Sirt1 Signaling Pathway

Our previous research showed that CD38 played vital roles in Ang-II induced hypertrophy and high fat diet induced heart injury. However, the role of CD38 in heart aging is still unknown. In the present study, we reported that CD38 knockdown significantly protected cardiomyocytes from D-galactose (D-...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Wang, Ling-Fang, Cao, Qing, Wen, Ke, Xiao, Yun-Fei, Chen, Ting-Tao, Guan, Xiao-Hui, Liu, Yu, Zuo, Li, Qian, Yi-Song, Deng, Ke-Yu, Xin, Hong-Bo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735286/
https://ncbi.nlm.nih.gov/pubmed/31551807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01125
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