CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac muscle. We previously observed that CD38 deficiency remarkably protects mouse embryonic fibroblasts (MEFs) from oxidative stress-induced injury. However, whether CD38 deficiency protects from I/R injury in...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Guan, Xiao-Hui, Liu, Xiao-Hong, Hong, Xuan, Zhao, Ning, Xiao, Yun-Fei, Wang, Ling-Fang, Tang, Ling, Jiang, Kai, Qian, Yi-Song, Deng, Ke-Yu, Ji, Guangju, Fu, Mingui, Xin, Hong-Bo
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983367/
https://ncbi.nlm.nih.gov/pubmed/27547294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7410257
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