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(18)F-Fluoroestradiol PET Imaging of Activating Estrogen Receptor-α Mutations in Breast Cancer
The purpose of this study was to determine the effect of estrogen receptor-α gene (ESR1) mutations at the tyrosine (Y) 537 amino acid residue within the ligand binding domain on (18)F-fluoroestradiol ((18)F-FES) binding and in vivo tumor uptake compared with wild-type (WT)-estrogen receptor α (ER)....
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| Publicado en: | J Nucl Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society of Nuclear Medicine
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6735277/ https://ncbi.nlm.nih.gov/pubmed/30850489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.224667 |
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