(18)F-Fluoroestradiol PET Imaging of Activating Estrogen Receptor-α Mutations in Breast Cancer

The purpose of this study was to determine the effect of estrogen receptor-α gene (ESR1) mutations at the tyrosine (Y) 537 amino acid residue within the ligand binding domain on (18)F-fluoroestradiol ((18)F-FES) binding and in vivo tumor uptake compared with wild-type (WT)-estrogen receptor α (ER)....

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Enregistré dans:
Détails bibliographiques
Publié dans:J Nucl Med
Auteurs principaux: Kumar, Manoj, Salem, Kelley, Michel, Ciara, Jeffery, Justin J., Yan, Yongjun, Fowler, Amy M.
Format: Artigo
Langue:Inglês
Publié: Society of Nuclear Medicine 2019
Sujets:
Oncology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735277/
https://ncbi.nlm.nih.gov/pubmed/30850489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.224667
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