Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans

Continuous laminar shear stress increases the process of autophagy, activates endothelial nitric oxide (NO) synthase phosphorylation at serine 1177 (p-eNOS(S1177)), and generates NO in bovine and human arterial endothelial cells (ECs) compared with static controls. However, the translational relevan...

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Dades bibliogràfiques
Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Park, Seul-Ki, La Salle, D. Taylor, Cerbie, James, Cho, Jae Min, Bledsoe, Amber, Nelson, Ashley, Morgan, David E., Richardson, Russell S., Shiu, Yan-Ting, Boudina, Sihem, Trinity, Joel D., Symons, J. David
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2019
Matèries:
Rapid Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734082/
https://ncbi.nlm.nih.gov/pubmed/30412436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00561.2018
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