Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans

Continuous laminar shear stress increases the process of autophagy, activates endothelial nitric oxide (NO) synthase phosphorylation at serine 1177 (p-eNOS(S1177)), and generates NO in bovine and human arterial endothelial cells (ECs) compared with static controls. However, the translational relevan...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Park, Seul-Ki, La Salle, D. Taylor, Cerbie, James, Cho, Jae Min, Bledsoe, Amber, Nelson, Ashley, Morgan, David E., Richardson, Russell S., Shiu, Yan-Ting, Boudina, Sihem, Trinity, Joel D., Symons, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Rapid Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734082/
https://ncbi.nlm.nih.gov/pubmed/30412436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00561.2018
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