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Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans

Continuous laminar shear stress increases the process of autophagy, activates endothelial nitric oxide (NO) synthase phosphorylation at serine 1177 (p-eNOS(S1177)), and generates NO in bovine and human arterial endothelial cells (ECs) compared with static controls. However, the translational relevan...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Park, Seul-Ki, La Salle, D. Taylor, Cerbie, James, Cho, Jae Min, Bledsoe, Amber, Nelson, Ashley, Morgan, David E., Richardson, Russell S., Shiu, Yan-Ting, Boudina, Sihem, Trinity, Joel D., Symons, J. David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734082/
https://ncbi.nlm.nih.gov/pubmed/30412436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00561.2018
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