Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans

Continuous laminar shear stress increases the process of autophagy, activates endothelial nitric oxide (NO) synthase phosphorylation at serine 1177 (p-eNOS(S1177)), and generates NO in bovine and human arterial endothelial cells (ECs) compared with static controls. However, the translational relevan...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Park, Seul-Ki, La Salle, D. Taylor, Cerbie, James, Cho, Jae Min, Bledsoe, Amber, Nelson, Ashley, Morgan, David E., Richardson, Russell S., Shiu, Yan-Ting, Boudina, Sihem, Trinity, Joel D., Symons, J. David
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Rapid Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734082/
https://ncbi.nlm.nih.gov/pubmed/30412436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00561.2018
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