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PPARα augments heart function and cardiac fatty acid oxidation in early experimental polymicrobial sepsis
Children with sepsis and multisystem organ failure have downregulated leukocyte gene expression of peroxisome proliferator-activated receptor-α (PPARα), a nuclear hormone receptor transcription factor that regulates inflammation and lipid metabolism. Mouse models of sepsis have likewise demonstrated...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6734063/ https://ncbi.nlm.nih.gov/pubmed/27881386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00457.2016 |
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