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Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes

Mutations of the Ras proteins HRAS, KRAS4A, KRAS4B, and NRAS are associated with a high percentage of all human cancers. The proteins are composed of highly homologous N-terminal catalytic or globular domains, plus C-terminal hypervariable regions (HVRs). Post-translational modifications of all RAS...

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Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Barklis, Eric, Stephen, Andrew G., Staubus, August O., Barklis, Robin Lid, Alfadhli, Ayna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733658/
https://ncbi.nlm.nih.gov/pubmed/31330153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.07.025
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