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LIPID BIOSENSOR INTERACTIONS WITH WILD TYPE AND MATRIX DELETION HIV-1 GAG PROTEINS

The matrix (MA) domain of the HIV-1 precursor Gag protein (PrGag) has been shown interact with the HIV-1 envelope (Env) protein, and to direct PrGag proteins to plasma membrane (PM) assembly sites by virtue of its affinity to phosphatidylinositol-4,5-bisphosphate (PI[4,5]P2). Unexpectedly, HIV-1 vir...

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Détails bibliographiques
Publié dans:Virology
Auteurs principaux: Barklis, Eric, Staubus, August O., Mack, Andrew, Harper, Logan, Barklis, Robin Lid, Alfadhli, Ayna
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911238/
https://ncbi.nlm.nih.gov/pubmed/29549788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.03.004
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