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Molecular basis for dyneinopathies reveals insight into dynein regulation and dysfunction

Cytoplasmic dynein plays critical roles within the developing and mature nervous systems, including effecting nuclear migration, and retrograde transport of various cargos. Unsurprisingly, mutations in dynein are causative of various developmental neuropathies and motor neuron diseases. These ‘dynei...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Marzo, Matthew G, Griswold, Jacqueline M, Ruff, Kristina M, Buchmeier, Rachel E, Fees, Colby P, Markus, Steven M
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733598/
https://ncbi.nlm.nih.gov/pubmed/31364990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47246
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